IFIT3 Monoclonal antibody, PBS Only
IFIT3 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human
Applications
WB, IHC, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2C8B10
Cat no : 67208-1-PBS
Synonyms
Validation Data Gallery
Product Information
67208-1-PBS targets IFIT3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | IFIT3 fusion protein Ag7518 |
Full Name | IFIT3 |
Calculated Molecular Weight | 56 kDa |
Observed Molecular Weight | 60 kDa |
GenBank Accession Number | BC004977 |
Gene Symbol | IFIT3 |
Gene ID (NCBI) | 3437 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IFIT3 (IFN-induced protein with tetratricopeptide repeats 3), also known as IFIT-4, ISG-60 or RIG-G, is a 56 kDa IFN induced protein. IFIT3 has been identified to be associated with strong IFN antiviral activity. Upon RNA virus infection, IFIT3 is significantly induced, ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IFN regulatory factor 3 (IRF3)-mediated gene expression. IFIT3 thus may serve as an important modulator in innate immunity, revealing a new function of the IFIT family proteins.