IER2 Polyclonal antibody, PBS Only

IER2 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 23849-1-PBS

Synonyms

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Validation Data Gallery

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  IHC staining of human liver using 23849-1-AP (same clone as 23849-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 23849-1-AP (IER2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23849-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 23849-1-AP (same clone as 23849-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 23849-1-AP (IER2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23849-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 23849-1-AP (same clone as 23849-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 23849-1-AP (IER2 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 23849-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 23849-1-AP (same clone as 23849-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 23849-1-AP (IER2 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 23849-1-PBS in a different storage buffer formulation.

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Product Information

23849-1-PBS targets IER2 in IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: IER2 fusion protein Ag20869
• Full Name: immediate early response 2
• Calculated Molecular Weight: 223 aa, 24 kDa
• GenBank Accession Number: BC072432
• Gene Symbol: IER2
• Gene ID (NCBI): 9592
• RRID: AB_2879339
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Ier2 (also called ETR101, Pip92, 3CH92 and CHX1, hereafter referred to as Ier2, regardless of species) is an immediate early gene (PMID: 2678945) that was originally found to be upregulated in fibroblasts upon their activation (PMID: 3841511). Immediate early genes are a group of genes that are rapidly induced in quiescent cells by proliferation- and migration-inducing stimuli. Ier2 may have a role in tumor cell motility and metastasis (PMID: 22120713).