Product Information
81728-1-PBS targets IBA1 in WB, IHC, IF-P, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | IBA1 fusion protein Ag1363 Predict reactive species |
Full Name | allograft inflammatory factor 1 |
Calculated Molecular Weight | 17 kDa |
Observed Molecular Weight | 17 kDa |
GenBank Accession Number | BC009474 |
Gene Symbol | IBA1 |
Gene ID (NCBI) | 199 |
ENSEMBL Gene ID | ENSG00000204472 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P55008 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IBA1 is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Expression of IBA1 is up-regulated in activated microglia following facial nerve axotomy, ischemia, and several brain diseases, thereby implicating it in the activated phenotypes of microglia.