HuR/ELAVL1 Recombinant antibody, PBS Only

HuR/ELAVL1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4L10

Cat no : 82690-2-PBS

Synonyms

ELAVL1, Hu antigen R, ELAV-like protein 1, ELAVL 1, ELAV1

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Validation Data Gallery

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  WB analysis using 82690-2-RR (same clone as 82690-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82690-2-RR (HuR/ELAVL1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82690-2-PBS in a different storage buffer formulation.

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Product Information

82690-2-PBS targets HuR/ELAVL1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: HuR/ELAVL1 fusion protein Ag2249
• Full Name: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
• Calculated Molecular Weight: 326 aa, 36 kDa
• Observed Molecular Weight: 30-37 kDa
• GenBank Accession Number: BC003376
• Gene Symbol: HuR/ELAVL1
• Gene ID (NCBI): 1994
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ELAVL1, also named as HUR, belongs to the RRM elav family. It is involved in 3'-UTR ARE-mediated MYC stabilization. ELAVL1 binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, ELAVL1 binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.