HUS1 Monoclonal antibody, PBS Only

HUS1 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67168-1-PBS
Clone No.1E8E9

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, Indirect ELISA

Checkpoint protein HUS1, hHUS1, HUS1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67168-1-PBS targets HUS1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen HUS1 fusion protein Ag28527 Predict reactive species
Full Name HUS1 checkpoint homolog (S. pombe)
Calculated Molecular Weight 32 kDa
Observed Molecular Weight 32 kDa
GenBank Accession NumberBC007013
Gene Symbol HUS1
Gene ID (NCBI) 3364
RRIDAB_2882464
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO60921
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Hus1 belongs to the Rad family, form a heterotrimeric clamp with Rad1and Rad9 that acts as a putative sensor for DNA damage. This complex plays an apical role in the DNA damage response, loss of a functional complex affects many downstream checkpoint pathways [PMID: 11340080]. It is also a key complex involved in the activation of the ATR pathway. 9-1-1 forms a ring-shaped heterotrimer, resembling the homotrimeric sliding clamp, proliferating cell nuclear antigen (PCNA) [PMID: 19535328].

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