HTR3A Polyclonal antibody, PBS Only

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  WB analysis using 29685-1-AP (same clone as 29685-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29685-1-AP (HTR3A antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29685-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 29685-1-AP (same clone as 29685-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 29685-1-AP (HTR3A antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 29685-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human small intestine using 29685-1-AP (same clone as 29685-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 29685-1-AP (HTR3A antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 29685-1-PBS in a different storage buffer formulation.

HTR3A Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 29685-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

29685-1-PBS targets HTR3A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: HTR3A fusion protein Ag31317
• Full Name: 5-hydroxytryptamine (serotonin) receptor 3A
• Calculated Molecular Weight: 55 kDa
• Observed Molecular Weight: 55 kDa
• GenBank Accession Number: BC002354
• Gene Symbol: HTR3A
• Gene ID (NCBI): 3359
• RRID: AB_2918338
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P46098
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

HTR3A (5-hydroxytryptamine receptor 3A, 5-HT3A) belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (5-HT, serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. So far, five distinct 5-HT3 receptor subunits (A-E) have been identified. HTR3A can form functional homomers or heteromers with HTR3B or HTR3C or HTR3D or HTR3E. 5-HT3 receptors are capable of mediating fast excitatory neurotransmission in the CNS and peripheral nervous system (PNS). (PMID: 23038271; 17073663)