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HTR3A Polyclonal antibody, PBS Only

HTR3A Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29685-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using HTR3A Polyclonal antibody (29685-1-AP)

    WB analysis using 29685-1-AP (same clone as 29685-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29685-1-AP (HTR3A antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29685-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human small intestine tissue using HTR3A Polyclonal antibody (29685-1-AP)

    IHC staining of human small intestine using 29685-1-AP (same clone as 29685-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 29685-1-AP (HTR3A antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 29685-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human small intestine tissue using HTR3A Polyclonal antibody (29685-1-AP)

    IHC staining of human small intestine using 29685-1-AP (same clone as 29685-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 29685-1-AP (HTR3A antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 29685-1-PBS in a different storage buffer formulation.

Product Information

29685-1-PBS targets HTR3A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HTR3A fusion protein Ag31317
Full Name 5-hydroxytryptamine (serotonin) receptor 3A
Calculated Molecular Weight 55 kDa
Observed Molecular Weight55 kDa
GenBank Accession NumberBC002354
Gene Symbol HTR3A
Gene ID (NCBI) 3359
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

HTR3A (5-hydroxytryptamine receptor 3A, 5-HT3A) belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (5-HT, serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. So far, five distinct 5-HT3 receptor subunits (A-E) have been identified. HTR3A can form functional homomers or heteromers with HTR3B or HTR3C or HTR3D or HTR3E. 5-HT3 receptors are capable of mediating fast excitatory neurotransmission in the CNS and peripheral nervous system (PNS). (PMID: 23038271; 17073663)