HPS5 Polyclonal antibody, PBS Only

HPS5 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13901-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of mouse liver using 13901-1-AP (same clone as 13901-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 13901-1-AP (HPS5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse spleen using 13901-1-AP (same clone as 13901-1-PBS)

  mouse spleen tissue were subjected to SDS PAGE followed by western blot with 13901-1-AP (HPS5 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 13901-1-AP (same clone as 13901-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 13901-1-AP (HPS5 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

• 

  IF Staining of MCF-7 using 13901-1-AP (same clone as 13901-1-PBS)

  Immunofluorescent analysis of MCF-7 cells, using HPS5 antibody 13901-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye). This data was developed using the same antibody clone with 13901-1-PBS in a different storage buffer formulation.

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Product Information

13901-1-PBS targets HPS5 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: HPS5 fusion protein Ag4867
• Full Name: Hermansky-Pudlak syndrome 5
• Calculated Molecular Weight: 1129 aa, 127 kDa
• Observed Molecular Weight: 135-141 kDa
• GenBank Accession Number: BC033640
• Gene Symbol: HPS5
• Gene ID (NCBI): 11234
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Hermansky-Pudlak syndrome 5 protein (HPS-5), also named Ruby-eye protein 2 homolog (Ru2), plays a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5.