HNF1B Recombinant antibody, PBS Only

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  WB analysis of MDCK using 84684-4-RR (same clone as 84684-4-PBS)

  MDCK cells were subjected to SDS PAGE followed by western blot with 84684-4-RR (HNF1B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84684-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84684-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84684-4-RR against Human HNF1B were performed. The affinity constant is 0.232 nM.

HNF1B {ptg:Brand} Recombinant Antibody for WB, Indirect ELISA

Cat No. 84684-4-PBS

Clone No.242120A9

Host / Isotype

Rabbit / IgG

Reactivity

human, canine

Applications

WB, Indirect ELISA

Synonyms

TCF2, HNF-1-beta, HNF-1B, HNF 1 beta, Hepatocyte nuclear factor 1-beta

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Product Information

84684-4-PBS targets HNF1B in WB, Indirect ELISA applications and shows reactivity with human, canine samples.

• Tested Reactivity: human, canine
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: HNF1B fusion protein Ag3232
• Full Name: HNF1 homeobox B
• Calculated Molecular Weight: 557 aa, 61 kDa
• Observed Molecular Weight: 58-65 kDa
• GenBank Accession Number: BC017714
• Gene Symbol: HNF1B
• Gene ID (NCBI): 6928
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P35680
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Hepatocyte nuclear factor-1-beta(HNF1B), or transcription factor-2(TCF2), is a member of the homeodomain-containing superfamily of transcription factors. Early expression of HNF1B(12533-1-AP) is seen in the kidney, liver, pancreas, thymus, lung, gut and genital tract. HNF1B can be a homodimer or a heterodimer with HNF1A. It's a transcription factor, probably by binding to the inverted palindrome 5'-GTTAATNATTAAC-3', and as a bookmarking factor that marks target genes for rapid transcriptional reactivation after mitosis.