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HLA-DMA Recombinant antibody, PBS Only (Detector)

HLA-DMA Uni-rAbTM Recombinant Antibody for Indirect ELISA, Cytometric bead array

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230155D3

Cat no : 82899-1-PBS

Synonyms

hCG_2001572, DMA protein MHC class II antigen Major histocompatibility complex, class II, DM alpha cDNA FLJ75740, highly similar to Homo sapiens major histocompatibility complex, class II, DM alpha, DMA protein, DMA, D6S222E

Validation Data Gallery

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  • Cytometric bead array standard curve of MP00018-1

    Cytometric bead array standard curve of MP00018-1

    Cytometric bead array standard curve ofMP00018-1, HLA-DMA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82899-5-PBS. Detection antibody: 82899-1-PBS. Standard: Ag2452. Range: 0.625-20 ng/mL.

  • Cytometric bead array standard curve of MP00018-3

    Cytometric bead array standard curve of MP00018-3

    Cytometric bead array standard curve ofMP00018-3, HLA-DMA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82899-3-PBS. Detection antibody: 82899-1-PBS. Standard: Ag2452. Range: 0.625-20 ng/mL.

Product Information

82899-1-PBS targets HLA-DMA as part of a matched antibody pair:

MP00018-1: 82899-5-PBS capture and 82899-1-PBS detection (validated in Cytometric bead array)

MP00018-3: 82899-3-PBS capture and 82899-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen HLA-DMA fusion protein Ag2452
Full Name major histocompatibility complex, class II, DM alpha
Calculated Molecular Weight 261 aa, 29 kDa
GenBank Accession NumberBC026279
Gene Symbol HLA-DMA
Gene ID (NCBI) 3108
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer 100% PBS pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). The class II molecules are composed of two non-covalently associated alpha and beta chains. HLA-DMA and HLA-DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.