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Product Information

11746-1-PBS targets HBP1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HBP1 fusion protein Ag2342 Predict reactive species
Full Name HMG-box transcription factor 1
Calculated Molecular Weight 514 aa, 58 kDa
Observed Molecular Weight 58 kDa
GenBank Accession NumberBC022329
Gene Symbol HBP1
Gene ID (NCBI) 26959
RRIDAB_2247970
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO60381
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

HMG-box protein 1 (HBP1) is a transcriptional repressor, and has a role in cell cycle progression and tumor suppression. Also it's a repressor of the cyclin D1 gene and inhibits the Wnt signaling pathway. Interaction with RB1 enhances it's binding to the H1F0 promoter . Disrupts the interaction between DNA and TCF4. This is a rabbit polyclonal antibody raised against part of C-terminus of HBP1 of human origin.

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