Product Information
11746-1-PBS targets HBP1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | HBP1 fusion protein Ag2342 Predict reactive species |
Full Name | HMG-box transcription factor 1 |
Calculated Molecular Weight | 514 aa, 58 kDa |
Observed Molecular Weight | 58 kDa |
GenBank Accession Number | BC022329 |
Gene Symbol | HBP1 |
Gene ID (NCBI) | 26959 |
RRID | AB_2247970 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | O60381 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
HMG-box protein 1 (HBP1) is a transcriptional repressor, and has a role in cell cycle progression and tumor suppression. Also it's a repressor of the cyclin D1 gene and inhibits the Wnt signaling pathway. Interaction with RB1 enhances it's binding to the H1F0 promoter . Disrupts the interaction between DNA and TCF4. This is a rabbit polyclonal antibody raised against part of C-terminus of HBP1 of human origin.