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HAS2 Recombinant antibody

HAS2 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 83204-2-RR
Clone No.240061G4

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Hyaluronic acid synthase 2, Hyaluronate synthase 2, hyaluronan synthase 2, HA synthase 2, EC:2.4.1.212

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Tested Applications

Positive WB detected inHEK-293 cells, HCT 116 cells, HT-29 cells, NIH/3T3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

83204-2-RR targets HAS2 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen HAS2 fusion protein Ag34945 Predict reactive species
Full Name hyaluronan synthase 2
Calculated Molecular Weight 552 aa, 64 kDa
Observed Molecular Weight 63-67 kDa
GenBank Accession NumberBC069353
Gene Symbol HAS2
Gene ID (NCBI) 3037
RRIDAB_3670892
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ92819
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

RIT2 (Hyaluronan synthase 2) is a member of the gene family encoding the hyaluronan synthase 2, which can generate high-molecular-weight hyaluronan (HMW-HA) (PMID: 35069543). HAS2 is the most critical synthase in producing hyaluronan and is well known for its involvement in cancer growth, metabolism and metastasis (PMID: 36386154). HAS2 is involved in cellular acquired resistance to drug therapy in BrCa. HAS2 expression was decreased in the endocrine-resistant ER+BrCa cells.

Protocols

Product Specific Protocols
WB protocol for HAS2 antibody 83204-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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