• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

HABP2 Polyclonal antibody, PBS Only

HABP2 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12863-1-PBS

Synonyms

Validation Data Gallery

Filter:
  • Immunohistochemistry (IHC) staining of human liver cancer tissue using HABP2 Polyclonal antibody (12863-1-AP)

    IHC staining of human liver cancer using 12863-1-AP (same clone as 12863-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12863-1-AP (HABP2 Antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12863-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using HABP2 Polyclonal antibody (12863-1-AP)

    IHC staining of human liver cancer using 12863-1-AP (same clone as 12863-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12863-1-AP (HABP2 Antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 12863-1-PBS in a different storage buffer formulation.

Product Information

12863-1-PBS targets HABP2 in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HABP2 fusion protein Ag3981
Full Name hyaluronan binding protein 2
Calculated Molecular Weight 560 aa, 63 kDa
GenBank Accession NumberBC031412
Gene Symbol HABP2
Gene ID (NCBI) 3026
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

HABP2 is also named as HGFAL, PHBP and belongs to the peptidase S1 family. It can activate coagulation factor VII and prourokinase and release the vasoactive peptide bradykinin by cleaving kininogen and is an important role in the regulation of the haemostasis system as well as fibroproliferative inflammatory processes (PMID:21655671). HABP2 is present as the 70 kDa inactive single chain precursor in human plasma and transforms to the active two chain form, 50 kDa heavy chain and 27 kDa light chain,and the 50 kDa heavy chain changes to two 26 kDa fragments, and 27 kDa light chain to 17 kDa and 8 kDa fragments, which are all bridged by disulfide linkages, by autocleavage(PMID:11217080).