GSTM5 Monoclonal antibody, PBS Only

GSTM5 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat, pig, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2E5C2

Cat no : 68210-1-PBS

Synonyms

glutathione S transferase mu 5, GST class mu 5, GSTM5, GSTM5 5, GTM5

---

Validation Data Gallery

• 

  WB analysis using 68210-1-Ig (same clone as 68210-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68210-1-Ig (GSTM5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68210-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68210-1-Ig (same clone as 68210-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68210-1-Ig (GSTM5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68210-1-PBS in a different storage buffer formulation.

• 

  WB analysis of pig liver using 68210-1-Ig (same clone as 68210-1-PBS)

  pig liver tissue were subjected to SDS PAGE followed by western blot with 68210-1-Ig (GSTM5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68210-1-PBS in a different storage buffer formulation.

---

Product Information

68210-1-PBS targets GSTM5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples.

• Tested Reactivity: Human, mouse, rat, pig, rabbit
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: GSTM5 fusion protein Ag6054
• Full Name: glutathione S-transferase mu 5
• Calculated Molecular Weight: 26 kDa
• Observed Molecular Weight: 26 kDa
• GenBank Accession Number: BC058881
• Gene Symbol: GSTM5
• Gene ID (NCBI): 2949
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

GSTM5, Glutathione S-transferases, belongs to eukaryotic and prokaryotic phase II metabolic isozymes family. It can catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for detoxification. GSTM5 undergo epigenetic repression in AMD (age-related macular degeneration) RPE/choroid, which may increase susceptibility to oxidative stress in AMD retinas (PMID: 22410570). GSTM5 was found in brain, lung and testis (PMID: 9230131).