GSDMD Recombinant antibody, PBS Only

GSDMD Uni-rAbTM Recombinant Antibody for WB, FC (Intra), Indirect ELISA
Cat No. 80918-1-PBS
Clone No.2N24

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, FC (Intra), Indirect ELISA

Gasdermin-D, gasderminD, Gasdermin domain-containing protein 1, gasdermin D, FKSG10

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

80918-1-PBS targets GSDMD in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen GSDMD fusion protein Ag14757 Predict reactive species
Full Name gasdermin D
Calculated Molecular Weight 484 aa, 53 kDa
Observed Molecular Weight50-53 kDa
GenBank Accession NumberBC008904
Gene Symbol GSDMD
Gene ID (NCBI) 79792
RRIDAB_2918919
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP57764
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

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