GPR87 Polyclonal antibody
GPR87 Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
IHC, ELISA
Conjugate
Unconjugated
Cat no : 25999-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive IHC detected in | mouse bladder tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
Application | Dilution |
---|---|
Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
25999-1-AP targets GPR87 in IHC, ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | GPR87 fusion protein Ag23214 |
Full Name | G protein-coupled receptor 87 |
GenBank Accession Number | BC132888 |
Gene Symbol | GPR87 |
Gene ID (NCBI) | 53836 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
G Protein-Coupled Receptor 87 (GPR87) is a GPCR, and it has been demonstrated to regulate the progression of several tumors (PMID:18183596). Studied reported that GPR87 promotes PDA (Pancreatic ductal adenocarcinoma) proliferation, angiogenesis, gemcitabine resistance, and tumorigenicity through activating the nuclear factor-kB (NF-kB) pathway (PMID:32405536). GPR87 is an independent prognostic factor for bladder cancer intravesical recurrence; it promotes bladder cancer cell proliferation and inhibits apoptosis. In addition, GPR87 was deorphanized and shown to be a lysophosphatidic acid (LPA) receptor (PMID:23752273).
Protocols
Product Specific Protocols | |
---|---|
IHC protocol for GPR87 antibody 25999-1-AP | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |