GPNMB Monoclonal antibody, PBS Only

GPNMB Monoclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 66926-1-PBS
Clone No.2B10B8

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, ELISA

UNQ1725/PRO9925, Transmembrane glycoprotein NMB, Osteoactivin, NMB, Hematopoietic growth factor inducible neurokinin-1 type

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66926-1-PBS targets GPNMB in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen GPNMB fusion protein Ag26747 Predict reactive species
Full Name glycoprotein (transmembrane) nmb
Calculated Molecular Weight 64 kDa
Observed Molecular Weight 64-70 kDa
GenBank Accession NumberBC011595
Gene Symbol GPNMB
Gene ID (NCBI) 10457
RRIDAB_2882253
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ14956
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

GPNMB also known as HGFIN, osteoactivin, and DC-HIL, is a type I membrane glycoprotein involved in various biological processes, including inflammation, invasion and metastasis of malignant tumors, cell differentiation, and tissue regeneration. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB acts as an osteogenic factor that stimulates osteoblast differentiation in vivo and in vitro.

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