GPD1 Recombinant antibody, PBS Only

GPD1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84800-4-PBS
Clone No.242359C4

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

GPD C, GPD 1, Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic, EC:1.1.1.8, cGPDH

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

84800-4-PBS targets GPD1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen GPD1 fusion protein Ag4278 Predict reactive species
Full Name glycerol-3-phosphate dehydrogenase 1 (soluble)
Calculated Molecular Weight 349 aa, 38 kDa
Observed Molecular Weight32 kDa
GenBank Accession NumberBC032234
Gene Symbol GPD1
Gene ID (NCBI) 2819
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP21695
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

GPD1 (Glycerol-3-phosphate dehydrogenase 1) is an important enzyme belonging to the NAD-dependent glycerol-3-phosphate dehydrogenase family. Its C-terminal structural domain contains multiple helical structures for binding the substrate DHAP, and its N-terminal structural domain contains a β-folded core for binding NADH. GPD1 catalyzes the conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotinamide adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+, and plays a key role in carbohydrate and lipid metabolism. GPD1 also works with mitochondrial glycerol-3-phosphate dehydrogenase to form a glycerophosphate shuttle system that facilitates the transfer of reducing equivalents from the cytoplasm to the mitochondria. Abnormal activity of GPD1 has been associated with a variety of metabolic disorders, such as obesity, hypertriglyceridemia, and GPD1 has been implicated in cancer, potentially acting as a tumor suppressor.

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