CD42b Polyclonal antibody

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• CD42b Polyclonal antibody (12860-1-AP)

CD42b Polyclonal Antibody for WB, ELISA

Cat No. 12860-1-AP Copied!

Publications (40)

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Host / Isotype

Rabbit / IgG

Reactivity

human, pig and More (2)

Applications

WB, IHC, IF, ELISA

Synonyms

Antigen CD42b-alpha, BSS, CD42b alpha, GP1B, GP1BA

• 

  WB analysis of human peripheral blood platelets using 12860-1-AP

  Human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 12860-1-AP (CD42b antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of pig peripheral blood leukocyte using 12860-1-AP

  pig peripheral blood leukocyte were subjected to SDS PAGE followed by western blot with 12860-1-AP (CD42b antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of human blood using 12860-1-AP

  human blood were subjected to SDS PAGE followed by western blot with 12860-1-AP (CD42b antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: Human peripheral blood platelets, pig peripheral blood leukocyte, human blood

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

12860-1-AP targets CD42b in WB, IHC, IF, ELISA applications and shows reactivity with human, pig samples.

• Tested Reactivity: human, pig
• Cited Reactivity: human, mouse, rat, pig
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag3893

  Product name: Recombinant human GP1BA protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 19-350 aa of BC027955

  Sequence: ICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDTEGDKVRATRTVVKFPTKAHTTPWGLFYSWSTASLDSQMPSSLHPTQESTK

• Full Name: glycoprotein Ib (platelet), alpha polypeptide
• Calculated Molecular Weight: 626 aa, 69 kDa
• Observed Molecular Weight: 145 kDa
• GenBank Accession Number: BC027955
• Gene Symbol: CD42b
• Gene ID (NCBI): 2811
• ENSEMBL Gene ID: ENSG00000185245
• RRID: AB_10644481
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P07359
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GP1BA, also named as CD42b , is a 145-kDa surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. It has a heterodimer form which composed of GP1BA and GP1BB.

Publications

What published studies show

CD42b (GP1BA) polyclonal antibody (Cat# 12860-1-AP) has 40 citations published in journals including Nature Communications, Science Translational Medicine, Science Advances, ACS Nano, Theranostics, Cancer Letters, Matter Today Bio, Platelets, Thrombosis Research, and others. Research fields span platelet biology and thrombosis, nanomedicine and drug delivery, cardiovascular disease (atherosclerosis, stroke), cancer, tissue engineering, inflammation/NETosis, and liver transplantation.

Automatically generated from the 40 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Bioact Mater; Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration; Authors - Wenshuai Li
mouse	ELISA	Nat Commun; HuR coordinates systemic aging through platelet infiltration.; Authors - Cihang Liu
		ACS Nano; Cryo-Shocked Platelet Coupled with ROS-Responsive Nanomedicine for Targeted Treatment of Thromboembolic Disease; Authors - Xingping Quan
human	WB	Trends Biotechnol; A regenerative and programmable iPSC-derived platelet platform for universal drug delivery and immunotherapy.; Authors - Lingna Wang
mouse	IF	Sci Transl Med; Dietary ketone body-escalated histone acetylation in megakaryocytes alleviates chemotherapy-induced thrombocytopenia; Authors - Sisi Xie
mouse	WB	J Nanobiotechnology; Platelet-rich plasma-derived extracellular vesicles delivered niraparib for ultrasound imaging and atherosclerosis treatment.; Authors - Weimin Fang