GLRX3 Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

GLRX3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11254-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 11254-1-AP (same clone as 11254-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11254-1-AP (GLRX3 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

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  WB analysis using 11254-1-AP (same clone as 11254-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11254-1-AP (GLRX3 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 11254-1-AP (same clone as 11254-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 11254-1-AP (GLRX3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 11254-1-AP (same clone as 11254-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 11254-1-AP (GLRX3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 11254-1-AP (same clone as 11254-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 11254-1-AP (GLRX3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

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Product Information

11254-1-PBS targets GLRX3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: GLRX3 fusion protein Ag1775
• Full Name: glutaredoxin 3
• Calculated Molecular Weight: 37 kDa
• Observed Molecular Weight: 37-40 kDa
• GenBank Accession Number: BC014372
• Gene Symbol: GLRX3
• Gene ID (NCBI): 10539
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

GLRX3(Glutaredoxin-3) is also named as PICOT, TXNL2. Mammalian glutaredoxin 3 is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals(PMID:20226171). Glrx3 could take a pivotal role in colon and lung cancer cells during the tumorigenesis, which is expressed in lung and colon cancers consistently and preferentially(PMID:19797004).