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FSTL1 Monoclonal antibody, PBS Only

FSTL1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G5G1

Cat no : 68528-1-PBS

Synonyms

FLJ50214, FLJ52277, follistatin like 1, Follistatin like protein 1, Follistatin related protein 1, FRP, FSL1, FSTL1

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using FSTL1 Monoclonal antibody (68528-1-Ig)

    WB analysis using 68528-1-Ig (same clone as 68528-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68528-1-Ig (FSTL1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68528-1-PBS in a different storage buffer formulation.

Product Information

68528-1-PBS targets FSTL1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen FSTL1 fusion protein Ag33795
Full Name follistatin-like 1
Calculated Molecular Weight 308 aa, 35 kDa
Observed Molecular Weight50-55 kDa
GenBank Accession NumberBC000055
Gene Symbol FSTL1
Gene ID (NCBI) 11167
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Follistatin-like 1 (FSTL1), initially discovered as a TGF-β1-induced gene, encodes a 308 amino acid secreted 45-55 kDa glycoprotein with a follistatin domain and two non-functional calcium-binding motifs. FSTL1 has been reported to be involved in the fate determination and maturation of epithelial cells. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure, demonstrating its functional importance. FSTL1 has been reported to exhibit both pro- and anti-inflammatory actions, with a specific anti-apoptotic and protective effect in cardiac or renal cell injury. Zwijsen et al. (1994) detected several isoforms of FSTL1 with molecular masses of 40 to 48 kD which differs from the 50- to 55-kD products detected by Tanaka et al. (1998) (OMIM).