Product Information
23718-1-PBS targets FOXQ1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | FOXQ1 fusion protein Ag20545 Predict reactive species |
Full Name | forkhead box Q1 |
Calculated Molecular Weight | 403 aa, 41 kDa |
Observed Molecular Weight | 42 kDa |
GenBank Accession Number | BC053850 |
Gene Symbol | FOXQ1 |
Gene ID (NCBI) | 94234 |
RRID | AB_2879310 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen Affinity purified |
UNIPROT ID | Q9C009 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
Forkhead box Q1 (FOXQ1, also known as HFH1), a member of the FOX gene family, contains the core DNA binding domain, whereas the flanking wings of FOXQ1 contribute to its sequence specificity. FOXQ1 is known to repress the promoter activity of smooth muscle-specific genes, such as telokin and SM22α. FOXQ1 expression is regulated by Hoxa1 in embryonic stem cells. [PMID:15722554, 8139574] As a transcription factor, FOXQ1 represses the promoter activity of smooth muscle-specific genes, such as telokin and SM22α, in A10 vascular muscle cells [PMID:10896677].