Product Information
66568-1-PBS targets FOXC1 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Peptide Predict reactive species |
Full Name | forkhead box C1 |
Calculated Molecular Weight | 57 kDa |
Observed Molecular Weight | 70-75 kDa |
GenBank Accession Number | NM_001453 |
Gene Symbol | FOXC1 |
Gene ID (NCBI) | 2296 |
RRID | AB_2881929 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q12948 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
FOXC1, also named as FKHL7 and FREAC3, binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3). Defects in FOXC1 are the cause of iridogoniodysgenesis anomaly (IGDA). Defects in FOXC1 are a cause of Peters anomaly.