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  • KD/KO Validated

FOXC1 Polyclonal antibody

FOXC1 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG


human, mouse





Cat no : 55365-1-AP


ARA, FKHL7, forkhead box C1, Forkhead box protein C1, Forkhead related protein FKHL7, FOXC1, FREAC 3, FREAC3, IGDA, IHG1, IRID1, RIEG3

Tested Applications

Positive WB detected inMCF-7 cells, HEK-293 cells, HepG2 cells
Positive IP detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:200-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55365-1-AP targets FOXC1 in WB, IP, IF, IHC, CoIP, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name forkhead box C1
Calculated Molecular Weight 57 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberNM_001453
Gene Symbol FOXC1
Gene ID (NCBI) 2296
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FOXC1, also named as FKHL7 and FREAC3, binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3). Defects in FOXC1 are the cause of iridogoniodysgenesis anomaly (IGDA). Defects in FOXC1 are a cause of Peters anomaly. This antibody is specific to FOXC1. Phosphorylation modification of Foxc1 protein may be responsible for the larger molecular weight of detection compared with theoretical molecular weight (PMID:27708239;16403239).


Product Specific Protocols
WB protocol for FOXC1 antibody 55365-1-APDownload protocol
IP protocol for FOXC1 antibody 55365-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




The osteoporosis risk variant rs9820407 at 3p22.1 acts as an allele-specific enhancer to regulate CTNNB1 expression by long-range chromatin loop formation.

Authors - Ya Wang
  • KD Validated

Tumour Biol

The long noncoding RNA FOXCUT promotes proliferation and migration by targeting FOXC1 in nasopharyngeal carcinoma.

Authors - Yu-Zhong Xu
  • KD Validated

Mol Med Rep

FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.

Authors - Qinchen Cao
  • KD Validated


Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1

Authors - Yufei Wang

J Oral Pathol Med

Single-cell RNA sequencing reveals tumor heterogeneity within salivary gland pleomorphic adenoma: A preliminary study

Authors - Xi-Qian Wang


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Sarah (Verified Customer) (08-20-2021)

I was sent 4 antibodies to try. You can see that JUN (1:1000) and NFKB1 (1:1000) worked, but FOXC1 (1:300) and HES1 (1:500) did not. I have shown that the cells express the mRNA for these proteins by qPCR.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:300
  • Cell Tissue Type: Tc28a2 immortalised chondrocytes
FOXC1 Antibody Western Blot validation (1:300 dilution) in Tc28a2 immortalised chondrocytes (Cat no:55365-1-AP)