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FMNL2 Monoclonal antibody, PBS Only

FMNL2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3E8C12

Cat no : 68551-1-PBS

Synonyms

FHOD2, FLJ37546, FMNL2, formin like 2, Formin like protein 2, KIAA1902

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using FMNL2 Monoclonal antibody (68551-1-Ig)

    WB analysis using 68551-1-Ig (same clone as 68551-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68551-1-Ig (FMNL2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68551-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of hTERT-RPE1 cells using FMNL2 Monoclonal antibody (68551-1-Ig)

    WB analysis of hTERT-RPE1 using 68551-1-Ig (same clone as 68551-1-PBS)

    hTERT-RPE1 cells were subjected to SDS PAGE followed by western blot with 68551-1-Ig (FMNL2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68551-1-PBS in a different storage buffer formulation.

Product Information

68551-1-PBS targets FMNL2 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen FMNL2 fusion protein Ag34164
Full Name formin-like 2
Observed Molecular Weight140-150 kDa
GenBank Accession NumberBC167159
Gene Symbol FMNL2
Gene ID (NCBI) 114793
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Formin-like 2 (FMNL2), also known as FRL3 or FHOD2, a member of the diaphanous-related formins, contains a GTPase-binding domain and autoregulatory domains, and is proposed to function as a downstream effector of Rho family guanosine triphosphatases (GTPases) (PMID:15950879). FMNL2 mRNA is expressed in many normal tissues and dysregulated in several cancers such as colorectal cancer, melanoma and involved in invasive behaviours and progression of cancer cells.