Product Information
12092-1-PBS targets FKBP7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | FKBP7 fusion protein Ag2733 Predict reactive species |
Full Name | FK506 binding protein 7 |
Calculated Molecular Weight | 259 aa, 30 kDa |
Observed Molecular Weight | 30 kDa |
GenBank Accession Number | BC009711 |
Gene Symbol | FKBP7 |
Gene ID (NCBI) | 51661 |
RRID | AB_2103418 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9Y680 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
FKBP7(FK506-binding protein 7) is also named as FKBP23 and belongs to immunophilin class of proteins family. This protein contains an N-terminal hydrophobic signal sequence, a PPIase motif, 2 EF-hand domains, and 2 putative N-glycosylation sites. The calculated molecular mass is about 25 kD, but becomes 33 kD following cleavage of the signal sequence(PMID:9806833). It could bind to BiP in ER in a process regulated by the concentration of Ca2+(PMID:22269648). It has 3 isoforms produced by alternative splicing.