FKBP7 Polyclonal antibody, PBS Only

FKBP7 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12092-1-PBS

Synonyms

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Validation Data Gallery

• 

  WB analysis of human lung using 12092-1-AP (same clone as 12092-1-PBS)

  human lung tissue were subjected to SDS PAGE followed by western blot with 12092-1-AP (FKBP7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human heart using 12092-1-AP (same clone as 12092-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 12092-1-AP (FKBP7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 12092-1-AP (same clone as 12092-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12092-1-AP (FKBP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12092-1-PBS in a different storage buffer formulation.

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Product Information

12092-1-PBS targets FKBP7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FKBP7 fusion protein Ag2733
• Full Name: FK506 binding protein 7
• Calculated Molecular Weight: 259 aa, 30 kDa
• Observed Molecular Weight: 30 kDa
• GenBank Accession Number: BC009711
• Gene Symbol: FKBP7
• Gene ID (NCBI): 51661
• RRID: AB_2103418
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

FKBP7(FK506-binding protein 7) is also named as FKBP23 and belongs to immunophilin class of proteins family. This protein contains an N-terminal hydrophobic signal sequence, a PPIase motif, 2 EF-hand domains, and 2 putative N-glycosylation sites. The calculated molecular mass is about 25 kD, but becomes 33 kD following cleavage of the signal sequence(PMID:9806833). It could bind to BiP in ER in a process regulated by the concentration of Ca2+(PMID:22269648). It has 3 isoforms produced by alternative splicing.