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  • KD/KO Validated

FKBP52 Polyclonal antibody

FKBP52 Polyclonal Antibody for WB, IP, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse and More (1)





Cat no : 10655-1-AP


51 kDa FK506 binding protein, 52 kDa FK506 binding protein, 52 kDa FKBP, 59 kDa immunophilin, FK506 binding protein 4, FK506 binding protein 4, 59kDa, FKBP 4, FKBP 52, FKBP4, FKBP51, FKBP52, FKBP59, HBI, HSP binding immunophilin, Hsp56, Immunophilin FKBP52, p52, p59, PPIase, PPIase FKBP4, Rotamase

Tested Applications

Positive WB detected inHeLa cells, PC-3 cells, Jurkat cells, NIH/3T3 cells, MCF-7 cells
Positive IP detected inHeLa cells
Positive IHC detected inhuman prostate cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inMCF-7 cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:8000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10655-1-AP targets FKBP52 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, chicken
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FKBP52 fusion protein Ag1019
Full Name FK506 binding protein 4, 59kDa
Calculated Molecular Weight 52 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC007924
Gene Symbol FKBP52
Gene ID (NCBI) 2288
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs, and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics, FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's, and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function, and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition, FKBP52 is likely to play a role in growth and development of the male genitalia.


Product Specific Protocols
WB protocol for FKBP52 antibody 10655-1-APDownload protocol
IHC protocol for FKBP52 antibody 10655-1-APDownload protocol
IF protocol for FKBP52 antibody 10655-1-APDownload protocol
IP protocol for FKBP52 antibody 10655-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer.

Authors - Alain Mangé
  • KD Validated

Clin Cancer Res

Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women.

Authors - Desmetz Caroline C

Mol Oncol

FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells.

Authors - Keisuke Maeda
  • KD Validated

Int J Mol Sci

Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations

Authors - Rika Kojima

J Cell Physiol

Multiple roles for peptidylglycine α-amidating monooxygenase in the response to hypoxia.

Authors - Vishwanatha K S Rao


The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly.

Authors - Martinez Natalia J NJ
  • KD Validated