FKBP11 Polyclonal antibody

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  WB analysis using 17467-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 17467-1-AP (FKBP11 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

FKBP11 Polyclonal Antibody for WB, ELISA

Cat No. 17467-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

19 kDa FK506 binding protein, 19 kDa FKBP, FK506 binding protein 11, FKBP 11, FKBP 19, FKBP11, FKBP19, PPIase FKBP11, Rotamase

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Tested Applications

• Positive WB detected in: Raji cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

17467-1-AP targets FKBP11 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FKBP11 fusion protein Ag11368
• Full Name: FK506 binding protein 11, 19 kDa
• Calculated Molecular Weight: 201 aa, 22 kDa
• Observed Molecular Weight: 24 kDa
• GenBank Accession Number: BC027973
• Gene Symbol: FKBP11
• Gene ID (NCBI): 51303
• RRID: AB_3669276
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NYL4
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FKBP11 (FK506 binding protein 11, also named FKBP19) was first described as predominantly expressed in secretory tissues including the pancreas and recent studies have suggested a role in beta cell survival under conditions of ER stress (PMID: 35456020). In addition, FKBP11 appears to play a role in osteoblasts and bone formation where it has been observed to associate with interferon-inducible transmembrane protein 5 (IFITM5) (PMID: 24058703).