FGF18 Polyclonal antibody, PBS Only

FGF18 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11495-1-PBS

Synonyms

---

Validation Data Gallery

• 

  IHC staining of mouse kidney using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse embryo using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse embryo using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse embryo using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse embryo using 11495-1-AP (same clone as 11495-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 11495-1-AP (FGF18 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 11495-1-AP (same clone as 11495-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using FGF18 antibody (11495-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 11495-1-PBS in a different storage buffer formulation.

---

Product Information

11495-1-PBS targets FGF18 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FGF18 fusion protein Ag2041
• Full Name: fibroblast growth factor 18
• Calculated Molecular Weight: 207 aa, 24 kDa
• GenBank Accession Number: BC006245
• Gene Symbol: FGF18
• Gene ID (NCBI): 8817
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.