FDPS Monoclonal antibody, PBS Only

FDPS Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3B8A7

Cat no : 67972-1-PBS

Synonyms

FDPS, FPP synthase, FPPS, FPS, KIAA1293

---

Validation Data Gallery

• 

  WB analysis using 67972-1-Ig (same clone as 67972-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67972-1-Ig (FDPS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 67972-1-PBS in a different storage buffer formulation.

---

Product Information

67972-1-PBS targets FDPS in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG2b
• Class: Monoclonal
• Type: Antibody
• Immunogen: FDPS fusion protein Ag9247
• Full Name: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
• Calculated Molecular Weight: 419 aa, 48 kDa
• Observed Molecular Weight: 38-39 kDa
• GenBank Accession Number: BC010004
• Gene Symbol: FDPS
• Gene ID (NCBI): 2224
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression.