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  • KD/KO Validated

FABP6 Polyclonal antibody

FABP6 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, ELISA, IF

Conjugate

Unconjugated

Cat no : 13781-1-AP

Synonyms

FABP6, Fatty acid binding protein 6, Gastrotropin, GT, I 15P, I BABP, I BALB, I BAP, ILBP, ILBP3, Ileal lipid binding protein, ILLBP, Intestinal 15 kDa protein



Tested Applications

Positive WB detected inmouse small intestine tissue
Positive IHC detected inhuman small intestine tissue, mouse small intestine tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13781-1-AP targets FABP6 in WB, IHC, ELISA, IF applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FABP6 fusion protein Ag4788
Full Name fatty acid binding protein 6, ileal
Calculated Molecular Weight 177 aa, 20 kDa
Observed Molecular Weight 14 kDa
GenBank Accession NumberBC022489
Gene Symbol FABP6
Gene ID (NCBI) 2172
RRIDAB_2877976
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Fatty acid binding protein 6 (FABP6, also known as the ileal bile acid binding protein IBABP) is regarded as a bile acid binding protein found in the distal portion of the small intestine and may be important in maintaining bile acid homeostasis(PMID: 25754072). FABP6 is reportedly up-regulated in colorectal cancer, it has been suggested as a link between bile acids and the risk of colorectal cancer(PMID: 17909007). And also, it was showed a potential drug target for the treatment of diabetes(PMID: 27500412). There are 2 isoforms of this protein,one of which is about 14 kDa we detected.

Protocols

Product Specific Protocols
WB protocol for FABP6 antibody 13781-1-APDownload protocol
IHC protocol for FABP6 antibody 13781-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

J Exp Med

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.

Authors - Yalong Wang
mouseWB

Biomaterials

MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.

Authors - Mingming Song
mouseWB

J Agric Food Chem

Novel Metabolic Regulation of Bile Acid Responses to Low Cholesterol in Whole-Grain-Diet-Fed Mice.

Authors - Jinxin Liu
humanWB,IHC

J Immunol Res

FABP6 Expression Correlates with Immune Infiltration and Immunogenicity in Colorectal Cancer Cells

Authors - Wenping Lian
  • KD Validated
humanWB,IHC,IF

Aging (Albany NY)

FABP6 serves as a new therapeutic target in esophageal tumor

Authors - Dengfeng Zhang
humanWB

Int Immunopharmacol

Melatonin alleviates necrotizing enterocolitis by reducing bile acid levels through the SIRT1/FXR signalling axis

Authors - Jiahao Lai