EXOG Polyclonal antibody

• Featured Product
• KD/KO Validated

EXOG Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

3

Cat no : 21523-1-AP

Synonyms

Endo G like 1, ENDOGL1, ENDOGL2, Endonuclease G like 1, ENGL, ENGL a, ENGL B, EXOG, Nuclease EXOG, mitochondrial

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Validation Data Gallery

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  WB analysis of mouse cerebellum using 21523-1-AP

  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 21523-1-AP (EXOG antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse cerebellum using 21523-1-AP

  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 21523-1-AP (EXOG antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse cerebellum tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 2 publications below

Product Information

The immunogen of 21523-1-AP is EXOG Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: EXOG fusion protein Ag16122
• Full Name: endo/exonuclease (5'-3'), endonuclease G-like
• Calculated Molecular Weight: 368 aa, 41 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC104212
• Gene Symbol: EXOG
• Gene ID (NCBI): 9941
• RRID: AB_10755302
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

Species	Application	Title
		Sci Adv; The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication.; Authors - Min Jiang
human	WB	PLoS One; Selective mitochondrial DNA degradation following double-strand breaks.; Authors - Amandine Moretton
rat	WB	J Mol Neurosci; PGC-1ɑ Mediated-EXOG, a Specific Repair Enzyme for Mitochondrial DNA, Plays an Essential Role in the Rotenone-Induced Neurotoxicity of PC12 Cells.; Authors - Jingsong Xiao ; KD Validated