EXO1 Monoclonal antibody, PBS Only

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  WB analysis using 68536-1-Ig (same clone as 68536-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68536-1-Ig (EXO1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68536-1-PBS in a different storage buffer formulation.

EXO1 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 68536-1-PBS

Clone No.2D11D1

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Synonyms

EXO1, EXOI, exonuclease 1, Exonuclease I, HEX1, hExo1, hExoI

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Product Information

68536-1-PBS targets EXO1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: EXO1 fusion protein Ag9253
• Full Name: exonuclease 1
• Calculated Molecular Weight: 94 kDa
• Observed Molecular Weight: 115-120 kDa
• GenBank Accession Number: BC007491
• Gene Symbol: EXO1
• Gene ID (NCBI): 9156
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: Q9UQ84
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

EXO1, also named as HEX1, is a 846 amino acid protein, which belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily. EXO1 is highly expressed in bone marrow, testis and thymus and at lower levels in colon, lymph nodes, ovary, placenta, prostate, small intestine, spleen and stomach. EXO1 as 5'->3' double-stranded DNA exonuclease, which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. EXO1 functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. The calculated molecular weight of EXO1 is 94 kDa, but the modified EXO1 protein is about 115 kDa.