ETV6 Monoclonal antibody, PBS Only

ETV6 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 67579-1-PBS
Clone No.2A5A2

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, ELISA

ETS related protein Tel1, ETS translocation variant 6, ets variant 6, ETV6, TEL, TEL/ABL, TEL1, Transcription factor ETV6

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


67579-1-Ig

Product Information

67579-1-PBS targets ETV6 in WB, IHC, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ETV6 fusion protein Ag30054 Predict reactive species
Full Name ets variant 6
Calculated Molecular Weight 452 aa, 53 kDa
Observed Molecular Weight60 kDa
GenBank Accession NumberBC043399
Gene Symbol ETV6
Gene ID (NCBI) 2120
RRIDAB_2918493
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP41212
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

Background Information

ETV6(ETS Variant Transcription Factor 6), also known as TEL, is a Protein Coding gene. ETV6 is a member of the ETS family of transcription factors encoded by the ETS variant 6 gene (ETV6), located on chromosome 12p13.2. ETV6 protein contains 3 domains: a) the pointed N-terminal (i.e. PNT) domain which forms oligomer partners with itself as well as other transcription factors (e.g. FLI1) and is required for ETV6's transcriptional repressing activity; b) the central regulatory domain; and c) the C-terminal DNA-binding domain(PMID: 22578774). ETV6 is highly expressed in early hematopoietic progenitor cells(HPCs) and is essential for hematopoiesis in the bone marrow(PMID: 31248877).

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