ESRRG Monoclonal antibody

ESRRG Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

ELISA

Conjugate

Unconjugated

CloneNo.

5E11B10

Cat no : 60115-1-Ig

Synonyms

---

Validation Data Gallery

• 

  WB analysis of MCF-7 using 60115-1-Ig

  MCF7 cells were subjected to SDS PAGE followed by western blot with 60115-1-Ig (ESRRG antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours.

---

Product Information

60115-1-Ig targets ESRRG in ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: ESRRG fusion protein Ag5127
• Full Name: estrogen-related receptor gamma
• Calculated Molecular Weight: 51 kDa
• Observed Molecular Weight: 51 kDa
• GenBank Accession Number: BC064700
• Gene Symbol: ESRRG
• Gene ID (NCBI): 2104
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Caprylic Acid/Ammonium Sulfate Precipitation
• Storage Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3), is a member of nuclear hormone receptor family of steroid hormone receptors. As an orphan nuclear receptor, it binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. It behaves as a constitutive activator of transcription. 4-hydroxytamoxifen and diethylstilbestrol may act as inverse agonists and deactivate ESRRG. It also seems to be the target of bisphenol A. This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human ESRRG.