EOMES/TBR2 Polyclonal antibody

EOMES/TBR2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


Human, Mouse, rat





Cat no : 28316-1-AP


EOMES, EOMES/TBR2, Eomesodermin homolog, T box brain protein 2, T brain 2, TBR 2, TBR2

Tested Applications

Positive WB detected inmouse brain tissue, rat brain tissue

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

28316-1-AP targets EOMES/TBR2 in WB, ELISA applications and shows reactivity with Human, Mouse, rat samples.

Tested Reactivity Human, Mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen EOMES/TBR2 fusion protein Ag27634
Full Name eomesodermin homolog (Xenopus laevis)
Calculated Molecular Weight 73 aa
Observed Molecular Weight 70-72 kDa
GenBank Accession NumberNM_001278182
Gene Symbol EOMES
Gene ID (NCBI) 8320
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

EOMES/TRB2 (also named Eomesodermin/Tbr2) encode T-box transcription factor expressed highly in the intermediate progenitor stage of the developing neuron. During migration of the neurons, radial glia divide and migrate towards the surface of the cerebral cortex, there are three stages of cellular development: radial glia, intermediate progenitors, and postmitotic projection neurons. Radial glia express Pax6, while intermediate progenitor cells express Eomesodermin/Tbr2, and postmitotic projection neurons express Tbr1 (PMID:15634788; PMID:16320258). This process also called neurogenesis, and demonstrated that Eomesodermin/Tbr2 has been implicated in neurodevelopment. According to the mouse model, several articles showed that EOMES/TRB2 KO mice having proliferating cells decreased and having smaller upper cortical layers and a smaller sub ventricular zone in the brain (PMID:18940588). What's more, Eomesodermin/Tbr2 has also been found participating in immune response (PMID:20713880).


Product Specific Protocols
WB protocol for EOMES/TBR2 antibody 28316-1-APDownload protocol
Standard Protocols
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