ENY2 Polyclonal antibody, PBS Only

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  WB analysis of PC-3 using 15778-1-AP (same clone as 15778-1-PBS)

  PC-3 cells were subjected to SDS PAGE followed by western blot with 15778-1-AP (ENY2 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15778-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 15778-1-AP (same clone as 15778-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 15778-1-AP (ENY2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15778-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 15778-1-AP (same clone as 15778-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 15778-1-AP (ENY2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15778-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

ENY2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 15778-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

15778-1-PBS targets ENY2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ENY2 fusion protein Ag8462
• Full Name: enhancer of yellow 2 homolog (Drosophila)
• Calculated Molecular Weight: 12 kDa
• Observed Molecular Weight: 10 kDa
• GenBank Accession Number: BC007870
• Gene Symbol: ENY2
• Gene ID (NCBI): 56943
• RRID: AB_2878184
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NPA8
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ENY2, also named as DC6, is involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. It is required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). The MW of ENY2 is about 10 kDa.