- Featured Product
- KD/KO Validated
ENY2 Polyclonal antibody, PBS Only
ENY2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
Cat no : 15778-1-PBS
Synonyms
Validation Data Gallery
Product Information
15778-1-PBS targets ENY2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | ENY2 fusion protein Ag8462 |
Full Name | enhancer of yellow 2 homolog (Drosophila) |
Calculated Molecular Weight | 12 kDa |
Observed Molecular Weight | 10 kDa |
GenBank Accession Number | BC007870 |
Gene Symbol | ENY2 |
Gene ID (NCBI) | 56943 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
ENY2, also named as DC6, is involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. It is required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). The MW of ENY2 is about 10 kDa.