EGFL7 Polyclonal antibody

• Featured Product
• KD/KO Validated

EGFL7 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

WB, IF, IHC, ELISA

Conjugate

Unconjugated

Publications

12

Cat no : 19291-1-AP

Synonyms

EGF like domain, multiple 7, EGF like protein 7, EGFL7, MEGF7, NOTCH4 like protein, RP11 251M1.2, Vascular endothelial statin, VE STATIN, ZNEU1

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Validation Data Gallery

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  IHC staining of human breast cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human breast cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human ovary tumor using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human ovary tumor using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human endometrial cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human endometrial cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 40x lens).

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Published Applications

• KD/KO: See 2 publications below
• WB: See 11 publications below
• IHC: See 4 publications below
• IF: See 1 publications below

Product Information

The immunogen of 19291-1-AP is EGFL7 Fusion Protein expressed in E. coli.

• Tested Reactivity: human
• Cited Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: EGFL7 fusion protein Ag6559
• Full Name: EGF-like-domain, multiple 7
• Calculated Molecular Weight: 273 aa, 30 kDa
• GenBank Accession Number: BC012377
• Gene Symbol: EGFL7
• Gene ID (NCBI): 51162
• RRID: AB_10643993
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Epidermal growth factor-like domain-containing protein 7 (EGFL7), also known as vascular endothelial statin, is an endothelial cell-derived secreted factor that regulates vascular tube formation. This protein may be involved in the growth and proliferation of tumor cells. Recent studies have reported elevated expression of EGFL7 in several tumors and cancer cell lines, including kidney tumors, malignant gliomas, hepatocellular carcinomas, and colon cancers.

Publications

Species	Application	Title
human	WB	Blood Adv; The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models.; Authors - Yousef Salama ; KD Validated
human	WB	Mol Ther Nucleic Acids; Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay.; Authors - Chunqing Yang
human	WB,IHC,IF	Front Oncol; Novel Expression of EGFL7 in Osteosarcoma and Sensitivity to Cisplatin.; Authors - Qing Liu
mouse,rat	WB	Sci China Life Sci; Role of EGFL7/EGFR-signaling pathway in migration and invasion of growth hormone-producing pituitary adenomas.; Authors - Qian Liu
human	WB	Hum Gene Ther; Attenuation of EGFL7 expression inhibits growth hormone-producing pituitary adenomas growth and invasion.; Authors - Qian Liu
human	WB,IHC	Tumour Biol; EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway.; Authors - Jianpeng Wang