EFCAB1 Polyclonal antibody

EFCAB1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 17276-1-AP

Synonyms

EF-hand calcium-binding domain-containing protein 1, CLXN, Calaxin

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Validation Data Gallery

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  IHC staining of human colon using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human colon using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 40x lens).

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  IHC staining of human liver using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human liver using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 40x lens).

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Tested Applications

• Positive IHC detected in: human colon tissue, human liver tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

17276-1-AP targets EFCAB1 in WB, IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: EFCAB1 fusion protein Ag11039
• Full Name: EF-hand calcium binding domain 1
• Calculated Molecular Weight: 211 aa, 24 kDa
• GenBank Accession Number: BC025676
• Gene Symbol: EFCAB1
• Gene ID (NCBI): 79645
• RRID: AB_2878375
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

EFCAB1, also known as Calaxin, is a gene that encodes a protein involved in the function of cilia and flagella, which are hair-like structures protruding from the surface of certain cells. Research indicates that EFCAB1 overexpression inhibits cell proliferation, migration, and invasion while promoting apoptosis in lung adenocarcinoma cells. This suggests that EFCAB1 could potentially serve as a biomarker for lung adenocarcinoma.

Publications

Species	Application	Title
human	WB	Andrology; A novel homozygous LRRC6 mutation causes male infertility with asthenozoospermia and primary ciliary dyskinesia in humans; Authors - Shengjia Shi