Product Information
67756-1-PBS targets EED in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | EED fusion protein Ag10369 Predict reactive species |
Full Name | embryonic ectoderm development |
Calculated Molecular Weight | 466 aa, 53 kDa |
Observed Molecular Weight | 50/53/46 kDa. |
GenBank Accession Number | BC068995 |
Gene Symbol | EED |
Gene ID (NCBI) | 8726 |
RRID | AB_2918524 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O75530 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. EED has three isoforms, with the molecular weight of isoforms 1/2/3: 50/53/46 kDa.