Dysbindin Polyclonal antibody, PBS Only

• 

  WB analysis of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse testis using 11132-1-AP (same clone as 11132-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human testis using 11132-1-AP (same clone as 11132-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

Dysbindin Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 11132-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

11132-1-PBS targets Dysbindin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Dysbindin fusion protein Ag1613
• Full Name: dystrobrevin binding protein 1
• Calculated Molecular Weight: 351 aa, 39 kDa
• Observed Molecular Weight: 48 kDa, 36 kDa
• GenBank Accession Number: BC011912
• Gene Symbol: Dysbindin
• Gene ID (NCBI): 84062
• RRID: AB_11182503
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q96EV8
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Dysbindin, encoded by DTNBP1 (dystrobrevin binding protein 1), is a synaptic protein which is expressed in diverse neuronal populations throughout the brain. Genetic variation in DTNBP1 is associated with schizophrenia. Reduced expression of dysbindin has been reported in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia cases. Several isoforms of dysbindin exist: 48-50 kDa of dysbindin-1A, 35-38 kDa of dysbindin-1B, and 30-32 kDa of dysbindin-1C. This antibody recognizes all of isoforms of dysbindin. (19617633)