Desmocollin 2 Monoclonal antibody, PBS Only

• 

  WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Raji using 60239-1-Ig (same clone as 60239-1-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

Desmocollin 2 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 60239-1-PBS

Clone No.1H8G1

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

ARVD11, Cadherin family member 2, CDHF2, desmocoilin, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3

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Product Information

60239-1-PBS targets Desmocollin 2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: Desmocollin 2 fusion protein Ag5450
• Full Name: desmocollin 2
• Calculated Molecular Weight: 100 kDa
• Observed Molecular Weight: 110 kDa
• GenBank Accession Number: BC063291
• Gene Symbol: Desmocollin 2
• Gene ID (NCBI): 1824
• RRID: AB_2881362
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q02487
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.