DUSP5 Polyclonal antibody, PBS Only

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  WB analysis using 30256-1-AP (same clone as 30256-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30256-1-AP (DUSP5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

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  IP experiment of A549 using 30256-1-AP (same clone as 30256-1-PBS)

  IP result of anti-DUSP5 (IP:30256-1-AP, 4ug; Detection:30256-1-AP 1:500) with A549 cells lysate 1200 ug. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

DUSP5 Polyclonal Antibody for WB, IP, Indirect ELISA

Cat No. 30256-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, Indirect ELISA

Synonyms

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Product Information

30256-1-PBS targets DUSP5 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: DUSP5 fusion protein Ag32997
• Full Name: dual specificity phosphatase 5
• Calculated Molecular Weight: 42kd
• Observed Molecular Weight: 42 kDa
• GenBank Accession Number: NM_004419
• Gene Symbol: DUSP5
• Gene ID (NCBI): 1847
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q16690
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

DUSP5 (Dual specificity protein phosphatase 5) is also named as VH3. DUSP5, a member of DUSPs superfamily, is located in the nucleus and plays crucially regulatory roles in the signaling pathway transduction (PMID: 34169608). DUSP5 promotes the osteogenic differentiation of mesenchymal stromal cells (MSCs) by repressing SMAD1 signaling pathway in a SCP1/2‐dependent manner (PMID: 34169608). DUSP5, which specifically dephosphorylates extracellular signal-regulated kinase (ERK1/2), blocks pulmonary vascular smooth muscle cell proliferation (PMID: 34142888). DUSP5, an ERK1/2-specific endogenous phosphatase, was expressed at low levels in CRC (PMID: 36526622). DUSP5, a member of the DUSP subfamily, is known to regulate cellular inflammation (PMID: 33361528).