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DSC2 Recombinant antibody, PBS Only

DSC2 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241084G9

Cat no : 84985-1-PBS

Synonyms

Desmocollin 2, Desmocollin 3, CDHF2, Cadherin family member 2, ARVD11

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of Caco-2 cells using DSC2 Recombinant antibody (84985-1-RR)

    IF Staining of Caco-2 using 84985-1-RR (same clone as 84985-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Caco-2 cells using DSC2 antibody (84985-1-RR, Clone: 241084G9 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84985-1-PBS in a different storage buffer formulation.

Product Information

84985-1-PBS targets DSC2 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen DSC2 fusion protein Ag4956
Full Name desmocollin 2
Calculated Molecular Weight 100 kDa
GenBank Accession NumberBC063291
Gene Symbol Desmocollin 2
Gene ID (NCBI) 1824
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelial and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in the DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.