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DRD4 Polyclonal antibody, PBS Only

DRD4 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28094-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse brain tissue using DRD4 Polyclonal antibody (28094-1-AP)

    WB analysis of mouse brain using 28094-1-AP (same clone as 28094-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 28094-1-AP (DRD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28094-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of pig brain tissue using DRD4 Polyclonal antibody (28094-1-AP)

    WB analysis of pig brain using 28094-1-AP (same clone as 28094-1-PBS)

    pig brain tissue were subjected to SDS PAGE followed by western blot with 28094-1-AP (DRD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28094-1-PBS in a different storage buffer formulation.

Product Information

28094-1-PBS targets DRD4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

Tested Reactivity human, mouse, pig
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DRD4 fusion protein Ag26930
Full Name dopamine receptor D4
Calculated Molecular Weight 44 kDa
Observed Molecular Weight 40-44 kDa
GenBank Accession NumberNM_000797
Gene Symbol DRD4
Gene ID (NCBI) 1815
RRIDAB_2881058
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The family of dopamine receptors (DRs) includes five G protein-coupled receptors (GPCRs)-DRD1, DRD2, DRD3, DRD4 and DRD5-with different anatomical distribution, expression levels, dopamine affinity, signal transduction, and effector targets (PMID:36523297). DRD4 (dopamine receptor D4) influences the postsynaptic action of dopamine and is implicated in many neurological processes, exhibits polymorphism and is one of the most studied genes in connection with psychiatric disorders (PMID:21873960). Moreover, DRD4 modulate glucose metabolism, and protect neurocytes from anoxia/reoxygenation (A/R) injury. Thus, DRD4 might regulate myocardial I/R injury in association with GLUT4-mediated glucose metabolism (PMID:33584304).