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DOCK1 Monoclonal antibody, PBS Only

DOCK1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C3F12

Cat no : 67296-1-PBS

Synonyms

ced5, dedicator of cytokinesis 1, DOCK1, DOCK180

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using DOCK1 Monoclonal antibody (67296-1-Ig)

    WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using DOCK1 Monoclonal antibody (67296-1-Ig)

    WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

Product Information

67296-1-PBS targets DOCK1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen DOCK1 fusion protein Ag18069
Full Name dedicator of cytokinesis 1
Calculated Molecular Weight 1865 aa, 215 kDa
Observed Molecular Weight 215 kDa
GenBank Accession NumberBC146857
Gene Symbol DOCK1
Gene ID (NCBI) 1793
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1