DFNA5 Recombinant antibody, PBS Only

DFNA5 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 83454-6-PBS
Clone No.240394D2

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Gasdermin-E, Gasdermin E, DFNA5/GSDME, GSDME, DFNA 5

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

83454-6-PBS targets DFNA5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen DFNA5 fusion protein Ag3746 Predict reactive species
Full Name deafness, autosomal dominant 5
Calculated Molecular Weight 496 aa, 55 kDa
Observed Molecular Weight55 kDa
GenBank Accession NumberBC019689
Gene Symbol DFNA5
Gene ID (NCBI) 1687
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO60443
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

DFNA5 (deafness, autosomal dominant 5), also known as GSDME or ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas. Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain. GSDME produced two GSDME fragments with MW of 35 kDa and 25 kDa.

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