DCTD Monoclonal antibody, PBS Only
DCTD Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3D2G12
Cat no : 68357-1-PBS
Synonyms
Validation Data Gallery
Product Information
68357-1-PBS targets DCTD in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | DCTD fusion protein Ag10245 |
Full Name | dCMP deaminase |
Calculated Molecular Weight | 178 aa, 20 kDa |
Observed Molecular Weight | 18-20 kDa |
GenBank Accession Number | BC001286 |
Gene Symbol | DCTD |
Gene ID (NCBI) | 1635 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
DCTD(Deoxycytidylate deaminase) is also named as dCMP deaminase and belongs to the cytidine and deoxycytidylate deaminase family. It catalyzes the deamination of dCMP to dUMP, thus providing the nucleotide substrate for thymidylate synthase. Control of deaminase activity at this juncture in deoxyribonucleotide metabolism is determined by the ratio of dCTP to dTTP in the cell, since the enzyme is allosterically activated by dCTP and inhibited by dTTP(PMID:7685356). It has 2 isoforms produced by alternative splicing and can exsit as a dimer(pMID:8798492).