Rat MCP-1/CCL2 Recombinant antibody, PBS Only (Detector)

MCP-1/CCL2 Uni-rAb^TM Recombinant Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

rat

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240341D11

Cat no : 83370-1-PBS

Synonyms

Ccl2, chemokine (C C motif) ligand 2, CCL-2, CCL 2, C-C motif chemokine 2

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Validation Data Gallery

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  Cytometric bead array standard curve of MP00390-1

  Cytometric bead array standard curve of MP00390-1, RAT MCP-1/CCL-2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83370-3-PBS. Detection antibody: 83370-1-PBS. Standard: Eg0397. Range: 0.313-20 ng/mL.

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Product Information

83370-1-PBS targets MCP-1/CCL2 as part of a matched antibody pair:

MP00390-1: 83370-3-PBS capture and 83370-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

• Tested Reactivity: rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Fusion Protein
• Full Name: chemokine (C-C motif) ligand 2
• Calculated Molecular Weight: 16 kDa
• GenBank Accession Number: NM_031530
• Gene Symbol: MCP-1/CCL2
• Gene ID (NCBI): 24770
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Monocyte chemoattractant protein-1 (MCP-1/CCL2) is one of the key chemokines that regulate migration and infiltration of monocytes/macrophages. Both CCL2 and its receptor CCR2 have been demonstrated to be induced and involved in various diseases. Migration of monocytes from the blood stream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as in response to inflammation.