Casein Kinase 1 Epsilon Polyclonal antibody, PBS Only

Casein Kinase 1 Epsilon Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11230-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of A431 using 11230-1-AP (same clone as 11230-1-PBS)

  A431 cells were subjected to SDS PAGE followed by western blot with 11230-1-AP (Casein Kinase 1 epsilon antibody at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 11230-1-AP (same clone as 11230-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 11230-1-AP (Casein Kinase 1 epsilon antibody at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11230-1-AP (Casein Kinase 1 epsilon antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11230-1-AP (Casein Kinase 1 epsilon antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 11230-1-AP (same clone as 11230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 11230-1-AP (Casein Kinase 1 epsilon antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

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Product Information

11230-1-PBS targets Casein Kinase 1 Epsilon in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Casein Kinase 1 Epsilon fusion protein Ag1742
• Full Name: casein kinase 1, epsilon
• Calculated Molecular Weight: 47 kDa
• Observed Molecular Weight: 46-52 kDa
• GenBank Accession Number: BC006490
• Gene Symbol: CK1 epsilon
• Gene ID (NCBI): 1454
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CSNK1E(Casein kinase I isoform epsilon) is also named as CKIe, CKI-epsilon and belongs to the casein kinase I subfamily. It plays a significant role in delaying the negative feedback signal within the transcription-translation-based autoregulatory loop that composes the core of the circadian mechanism and makes an ideal target for pharmaceutical compounds influencing circadian rhythms, sleep, and jet lag, as well as other physiologic and metabolic processes under circadian regulation(PMID:10775102). It can be autophosphorylated(PMID:19690332).