CYP7A1 Polyclonal antibody, PBS Only
CYP7A1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
Cat no : 18054-1-PBS
Synonyms
Validation Data Gallery
Product Information
18054-1-PBS targets CYP7A1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | CYP7A1 fusion protein Ag12572 |
Full Name | cytochrome P450, family 7, subfamily A, polypeptide 1 |
Calculated Molecular Weight | 504 aa, 58 kDa |
Observed Molecular Weight | 58 kDa |
GenBank Accession Number | BC101777 |
Gene Symbol | CYP7A1 |
Gene ID (NCBI) | 1581 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CYP7A1 (Cytochrome P450 Family 7 Subfamily A Member 1), is a cholesterol 7alpha-hydroxylase, catalyzing the first and rate-limiting step in the neutral or classic pathway for bile acid biosynthesis. CYP7A1 is a postulated gene modifier of colorectal cancer risk and target for the therapeutic bile acid, ursodeoxycholic acid (UDCA). The CYP7A1 enzyme controls the rate-limiting step of the catabolism of cholesterol into bile acids in the liver.